Promethazine with Codeine Oral Remedy contains codeine, a Agenda V managed substance. As an opioid, Promethazine with Codeine Oral Alternative exposes consumers on the threats of dependancy, abuse, and misuse [see DRUG ABUSE AND DEPENDENCE (nine)], which can cause overdose and death [seeOVERDOSAGE (10)]. Reserve Promethazine with Codeine Oral Answe